General Information

    • DRAMP ID

    • DRAMP00266

    • Peptide Name

    • Putative antimicrobial protein 2 (Ls-AMP2; Plant defensin)

    • Source

    • Lippia sidoides (Pepper-rosmarin)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • SPPEAAYGPGNTNSDSGDK

    • Sequence Length

    • 19

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

      • Fungi: Botrytis cinerea.

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00266 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00266.

Physicochemical Information

    • Formula

    • C76H114N22O33

    • Absent Amino Acids

    • CFHILMQRVW

    • Common Amino Acids

    • GPS

    • Mass

    • 1863.87

    • PI

    • 4.03

    • Basic Residues

    • 1

    • Acidic Residues

    • 3

    • Hydrophobic Residues

    • 2

    • Net Charge

    • -2

    • Boman Index

    • -49.55

    • Hydrophobicity

    • -1.484

    • Aliphatic Index

    • 10.53

    • Half Life

      • Mammalian:1.9 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 1490

    • Absorbance 280nm

    • 82.78

    • Polar Residues

    • 10

DRAMP00266

DRAMP00266 chydropathy plot

Comments Information

    • Function

    • May possess antifungal activity.

    • Caution

    • Antifungal activity was tested using a fraction containing a number of different peptides. It is not clear which peptide actually has antifungal activity.

Literature Information

  • ·Literature 1

    • Title

    • Identification of botryticidal proteins with similarity to NBS-LRR proteins in rosemary pepper (Lippia sidoides Cham.) flowers.

    • Reference

    • Protein J. 2011 Jan;30(1):32-38.

    • Author

    • Moreira JS, Almeida RG, Tavares LS, Santos MO, Viccini LF, Vasconcelos IM, Oliveira JT, Raposo NR, Dias SC, Franco OL.