• DRAMP ID

    • DRAMP00270
    • Peptide Name

    • Osmotin (CpOsm; Plant defensin)
    • Source

    • Calotropis procera (Roostertree) (Asclepias procera)
    • Family

    • Belongs to the thaumatin family
    • Gene

    • Not found
    • Sequence

    • ATFTIRNNCPYTIWAAAVPGGGRRLNSGGTWTINVAPGTA
    • Sequence Length

    • 40
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Antifungal
    • Target Organism

      • Fungi: Fusarium solani (IC50=67.0 µg/ml), Colletotrichum gloeosporioides (IC50=32.1 µg/ml), Neurospora isolate (IC50=57.5 µg/ml).
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP00270 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP00270.
    • Formula

    • C183H283N55O53S
    • Absent Amino Acids

    • DEHKMQ
    • Common Amino Acids

    • AGT
    • Mass

    • 4133.66
    • PI

    • 10.76
    • Basic Residues

    • 3
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 15
    • Net Charge

    • +3
    • Boman Index

    • -37.1
    • Hydrophobicity

    • -0.025
    • Aliphatic Index

    • 68.5
    • Half Life

      • Mammalian:4.4 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 12490
    • Absorbance 280nm

    • 320.26
    • Polar Residues

    • 19

DRAMP00270

DRAMP00270 chydropathy plot
    • Function

    • Has antifungal activity.
    • Miscellaneous

    • On the 2D-gel the determined pI of isoform 1 is
  • ·Literature 1
    • Title

    • Osmotin purified from the latex of Calotropis procera: Biochemical characterization, biological activity and role in plant defense.
    • Reference

    • Plant Physiol Biochem. 2011 Jul;49(7):738-743.
    • Author

    • de Freitas CD, Nogueira FC, Vasconcelos IM, Oliveira JT, Domont GB, Ramos MV.