General Information

    • DRAMP ID

    • DRAMP00271

    • Peptide Name

    • Osmotin-like protein (Thaumatin-like protein; Plant defensin)

    • Source

    • Hevea brasiliensis (Para rubber tree) (Siphonia brasiliensis)

    • Family

    • Belongs to the thaumatin family

    • Gene

    • Not found

    • Sequence

    • ATFTIRNNXPYTVWAAASPGGGRRLDMARIWGRTNXNFD

    • Sequence Length

    • 39

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00271 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00271.

Physicochemical Information

    • Formula

    • C183H274N58O50S

    • Absent Amino Acids

    • CEHKQ

    • Common Amino Acids

    • AR

    • Mass

    • 4377.3

    • PI

    • 11.42

    • Basic Residues

    • 5

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 13

    • Net Charge

    • +3

    • Boman Index

    • -87.84

    • Hydrophobicity

    • -0.551

    • Aliphatic Index

    • 50.26

    • Half Life

      • Mammalian:4.4 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 12490

    • Absorbance 280nm

    • 328.68

    • Polar Residues

    • 14

DRAMP00271

DRAMP00271 chydropathy plot

Comments Information

    • Function

    • May be an important antifungal protein.

    • PTM

    • Contains intrachain disulfide bonds.

Literature Information

  • ·Literature 1

    • Title

    • Enzymic and structural studies on processed proteins from the vacuolar (lutoid-body) fraction of latex of Hevea brasiliensis.

    • Reference

    • Plant Physiol. Biochem. 2001;39:1047-1055.

    • Author

    • Subroto T, de Vries H, Schuringa J.J, Soedjanaatmadja U.M.S, Hofsteenge J, Jekel P.A, Beintema J.J.