General Information

    • DRAMP ID

    • DRAMP00272

    • Peptide Name

    • Thaumatin-like protein (Plants)

    • Source

    • Castanopsis chinensis (Chinese chinquapin) (Kweilin chestnut)

    • Family

    • Belongs to the thaumatin family

    • Gene

    • Not found

    • Sequence

    • AKITFTNNHPRTIWP

    • Sequence Length

    • 15

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal, Antiviral

    • Target Organism

      • Fungi: Botrytis cinerea, Fusarium oxysporum (IC50=0.5 µM), Mycosphaerella arachidicola, Psylla piricola.
      • HIV-1 reverse transcriptase (IC50=1.6 µM).

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00272 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00272.

Physicochemical Information

    • Formula

    • C83H126N24O21

    • Absent Amino Acids

    • CDEGLMQSVY

    • Common Amino Acids

    • T

    • Mass

    • 1796.06

    • PI

    • 11

    • Basic Residues

    • 3

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 5

    • Net Charge

    • +3

    • Boman Index

    • -29.16

    • Hydrophobicity

    • -0.747

    • Aliphatic Index

    • 58.67

    • Half Life

      • Mammalian:4.4 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 5500

    • Absorbance 280nm

    • 392.86

    • Polar Residues

    • 5

DRAMP00272

Comments Information

    • Comment

    • No comments found on DRAMP database

Literature Information

  • ·Literature 1

    • Title

    • Isolation of a large thaumatin-like antifungal protein from seeds of the Kweilin chestnut Castanopsis chinensis.

    • Reference

    • Biochem Biophys Res Commun. 2003 Feb 7;301(2):364-370.

    • Author

    • Chu KT, Ng TB.