General Information

    • DRAMP ID

    • DRAMP00314

    • Peptide Name

    • Endochitinase 3 (Plant defensin)

    • Source

    • Taxus baccata (English yew)

    • Family

    • Belongs to the glycosyl hydrolase 30 family (Chitinase class I subfamily)

    • Gene

    • Not found

    • Sequence

    • MYDESTGYSSALK

    • Sequence Length

    • 13

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00314 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00314.

Physicochemical Information

    • Formula

    • C62H94N14O24S

    • Absent Amino Acids

    • CFHINPQRVW

    • Common Amino Acids

    • S

    • Mass

    • 1451.57

    • PI

    • 4.37

    • Basic Residues

    • 1

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 2

    • Net Charge

    • -1

    • Boman Index

    • -24.11

    • Hydrophobicity

    • -0.731

    • Aliphatic Index

    • 37.69

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 2980

    • Absorbance 280nm

    • 248.33

    • Polar Residues

    • 7

DRAMP00314

Comments Information

    • Function

    • Defense against chitin containing fungal pathogens.

    • Catalytic activity

    • Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.

Literature Information

  • ·Literature 1

    • Title

    • Analysis of the soluble cell wall proteome of gymnosperms.

    • Reference

    • J Plant Physiol. 2009 May 15;166(8):831-843.

    • Author

    • Uzal EN, Gómez-Ros LV, Hernández JA, Pedreño MA, Cuello J, Ros Barceló A.