General Information

    • DRAMP ID

    • DRAMP00319

    • Peptide Name

    • Endochitinase (Plant defensin)

    • Source

    • Actinidia chinensis (Kiwi) (Yangtao)

    • Family

    • Belongs to the glycosyl hydrolase 35 family (Chitinase class I subfamily)

    • Gene

    • Not found

    • Sequence

    • ENCGRQAG

    • Sequence Length

    • 8

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • IgE

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00319 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00319.

Physicochemical Information

    • Formula

    • C30H51N13O13S

    • Absent Amino Acids

    • DFHIKLMPSTVWY

    • Common Amino Acids

    • G

    • Mass

    • 833.87

    • PI

    • 6.09

    • Basic Residues

    • 1

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 1

    • Net Charge

    • 0

    • Boman Index

    • -28.94

    • Hydrophobicity

    • -1.438

    • Aliphatic Index

    • 12.5

    • Half Life

      • Mammalian:1 hour
      • Yeast:30 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 4

DRAMP00319

Comments Information

    • Function

    • Defense against chitin containing fungal pathogens (By similarity).

    • Catalytic activity

    • Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.

    • Allergenic properties

    • Causes an allergic reaction in human.

    • Domian

    • Contains 1 chitin-binding type-1 domain.

Literature Information

  • ·Literature 1

    • Title

    • Suicide in Norway. Changes in the 20th century with special emphasis on the development during the last 20 years.

    • Reference

    • Tidsskr Nor Laegeforen. 1992 Jan 10;112(1):38-42.

    • Author

    • Rygnestad T.