General Information

    • DRAMP ID

    • DRAMP00331

    • Peptide Name

    • Pathogenesis-related protein (PRP; Plant defensin)

    • Source

    • Foeniculum vulgare (Fennel)

    • Family

    • Belongs to the BetVI family

    • Gene

    • Not found

    • Sequence

    • GVQKSEVVITSA

    • Sequence Length

    • 12

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Unknown

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • IgE

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00331 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00331.

Physicochemical Information

    • Formula

    • C52H92N14O19

    • Absent Amino Acids

    • CDFHLMNPRWY

    • Common Amino Acids

    • V

    • Mass

    • 1217.38

    • PI

    • 6

    • Basic Residues

    • 1

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 5

    • Net Charge

    • 0

    • Boman Index

    • -7.48

    • Hydrophobicity

    • 0.442

    • Aliphatic Index

    • 113.33

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 0

    • Absorbance 280nm

    • 0

    • Polar Residues

    • 4

DRAMP00331

Comments Information

    • Function

    • Probably involved in the defense reaction of plants against pathogens (By similarity).

    • Allergenic properties

    • Causes an allergic reaction in human.

Literature Information

  • ·Literature 1

    • Title

    • Fennel allergy is a lipid-transfer protein (LTP)-related food hypersensitivity associated with peach allergy.

    • Reference

    • J Agric Food Chem. 2013 Jan 23;61(3):740-746.

    • Author

    • Pastorello EA, Farioli L, Stafylaraki C, Scibilia J, Giuffrida MG, Mascheri A, Piantanida M, Baro C, Primavesi L, Nichelatti M, Schroeder JW, Pravettoni V.