General Information
-
DRAMP ID
- DRAMP00342
-
Peptide Name
- Antifungal protein R (Plant defensin)
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Source
- Hordeum vulgare (Barley)
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- ATITVVNRCSYTVWPGALPGGGVRLDPGQRWALNMPAGTAGAAV
-
Sequence Length
- 44
-
UniProt Entry
- P33044
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Protein Existence
- Protein level
Activity Information
-
Biological Activity
- Antimicrobial, Antifungal
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Target Organism
-
- Fungi: Trichoderma viridae, Candida albicans.
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
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Structure
- Not found
-
Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP00342.
Physicochemical Information
-
Formula
- C197H312N58O56S2
Absent Amino Acids
- EFHK
Common Amino Acids
- AG
Mass
- 4453.12
PI
- 9.5
Basic Residues
- 3
Acidic Residues
- 1
Hydrophobic Residues
- 18
Net Charge
- +2
-
Boman Index
- -18.7
Hydrophobicity
- 0.239
Aliphatic Index
- 84.32
Half Life
-
- Mammalian:4.4 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 12490
Absorbance 280nm
- 290.47
Polar Residues
- 16
DRAMP00342
Comments Information
Function
- Has antifungal activity. Inhibits the growth of Trichoderma viridae and Candida albicans.
Literature Information
- ·Literature 1
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Title
- Two antifungal thaumatin-like proteins from barley grain.
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Pubmed ID
- 1936240
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Reference
- FEBS Lett. 1991 Oct 7;291(1):127-131.
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Author
- Hejgaard J, Jacobsen S, Svendsen I.