General Information

    • DRAMP ID

    • DRAMP00360

    • Peptide Name

    • Non-specific lipid-transfer protein 1 (LTP 1; Plants)

    • Source

    • Nigella sativa (Black cumin)

    • Family

    • Belongs to the plant LTP family

    • Gene

    • Not found

    • Sequence

    • ISCQDVKQSLAPCLPYVTGRAPKPA

    • Sequence Length

    • 25

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

      • Fungi: Fusarium oxysporum and Phytophthora infestans.

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Lipid-binding

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00360 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00360.

Physicochemical Information

    • Formula

    • C116H192N32O34S2

    • Absent Amino Acids

    • EFHMNW

    • Common Amino Acids

    • P

    • Mass

    • 2643.11

    • PI

    • 8.86

    • Basic Residues

    • 3

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 8

    • Net Charge

    • +2

    • Boman Index

    • -23.56

    • Hydrophobicity

    • -0.092

    • Aliphatic Index

    • 82

    • Half Life

      • Mammalian:20 hour
      • Yeast:30 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 1615

    • Absorbance 280nm

    • 67.29

    • Polar Residues

    • 7

DRAMP00360

DRAMP00360 chydropathy plot

Comments Information

    • Function

    • Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.

Literature Information

  • ·Literature 1

    • Title

    • Isolation of the lipid-transporting protein Ns-LTP1 from seeds of the garden fennel flower (Nigella sativa).

    • Reference

    • Bioorg Khim. 2009 May-Jun;35(3):344-349.

    • Author

    • Oshchepkova IuI, Veshkurova ON, Rogozhin EA, Musoliamov AKh, Smirnov AN, Odintsova TI, Egorov TsA, Grishin EV, Salikhov ShI.