General Information
-
DRAMP ID
- DRAMP00379
-
Peptide Name
- Antifungal protein 3 (CW-3; Plants)
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Source
- Malva parviflora (Little mallow) (Cheeseweed mallow)
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- PEDPQRRYQEEQRRE
-
Sequence Length
- 15
-
UniProt Entry
- P83137
-
Protein Existence
- Protein level
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Antifungal
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Target Organism
-
- Fungi: Phytophthora infestans.
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP00379.
Physicochemical Information
-
Formula
- C82H130N30O30
Absent Amino Acids
- ACFGHIKLMNSTVW
Common Amino Acids
- ER
Mass
- 2016.12
PI
- 5.01
Basic Residues
- 4
Acidic Residues
- 5
Hydrophobic Residues
- 0
Net Charge
- -1
-
Boman Index
- -112.4
Hydrophobicity
- -3.367
Aliphatic Index
- 0
Half Life
-
- Mammalian:>20 hour
- Yeast:>20 hour
- E.coli:?
Extinction Coefficient Cystines
- 1490
Absorbance 280nm
- 106.43
Polar Residues
- 1
DRAMP00379
Comments Information
Function
- Possesses antifungal activity.
Miscellaneous
- Antimicrobial activity is not affected by salt concentration.
Literature Information
- ·Literature 1
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Title
- Purification and characterization of three antifungal proteins from cheeseweed (Malva parviflora).
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Pubmed ID
- 11302747
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Reference
- Biochem Biophys Res Commun. 2001 Apr 20;282(5):1224-1228.
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Author
- Wang X, Bunkers GJ, Walters MR, Thoma RS.