General Information
-
DRAMP ID
- DRAMP00381
-
Peptide Name
- IWF4 (Plants)
-
Source
- Beta vulgaris (Sugar beet)
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- SGECNMYGRCPPGYCCSKFGYCGGVRAYCG
-
Sequence Length
- 30
-
UniProt Entry
- No entry found
-
Protein Existence
- Not found
Activity Information
-
Biological Activity
- Antimicrobial, Antifungal
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Target Organism
-
- Fungi: Cercospora beticola (IC50<2 µg/mL).
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Chitin-binding
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP00381.
Physicochemical Information
-
Formula
- C133H194N38O40S7
Absent Amino Acids
- DHILQTW
Common Amino Acids
- G
Mass
- 3189.65
PI
- 8.27
Basic Residues
- 3
Acidic Residues
- 1
Hydrophobic Residues
- 3
Net Charge
- +2
-
Boman Index
- -30.76
Hydrophobicity
- -0.233
Aliphatic Index
- 13
Half Life
-
- Mammalian:1.9 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 6335
Absorbance 280nm
- 218.45
Polar Residues
- 20
DRAMP00381
Comments Information
Tissue specificity
- IWF4 mRNA is expressed in the aerial parts of the plant only, with a constitutive expression in young and mature leaves and in young flowers.
Literature Information
- ·Literature 1
-
Title
- Characterization of a new antifungal chitin-binding peptide from sugar beet leaves.
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Pubmed ID
- 9008390
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Reference
- Plant Physiol. 1997 Jan;113(1):83-91.
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Author
- Nielsen KK, Nielsen JE, Madrid SM, Mikkelsen JD.