General Information
-
DRAMP ID
- DRAMP00382
-
Peptide Name
- Datucin (Glycopeptide; Plants)
-
Source
- Datura stramonium
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- TFPKCAPTRPPGPKPCDINNFKSKFWHIWRA
-
Sequence Length
- 31
-
UniProt Entry
- No entry found
-
Protein Existence
- Not found
Activity Information
-
Biological Activity
- Antimicrobial, Antifungal
-
Target Organism
- No MICs found in DRAMP database
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP00382.
Physicochemical Information
-
Formula
- C170H251N47O39S2
Absent Amino Acids
- ELMQVY
Common Amino Acids
- P
Mass
- 3641.27
PI
- 10.06
Basic Residues
- 7
Acidic Residues
- 1
Hydrophobic Residues
- 9
Net Charge
- +6
-
Boman Index
- -56.68
Hydrophobicity
- -0.848
Aliphatic Index
- 31.61
Half Life
-
- Mammalian:7.2 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 11125
Absorbance 280nm
- 370.83
Polar Residues
- 8
DRAMP00382
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
-
Title
- A Novel Hydroxyproline Rich Glycopeptide from Pericarp of Datura stramonium: Proficiently Eradicate the Biofilm of Antifungals Resistant Candida albicans.
-
Pubmed ID
- 23193597
-
Reference
- Biopolymers 2012; 98(4):332-337.
-
Author
- Mandal SM.