General Information

    • DRAMP ID

    • DRAMP00386

    • Peptide Name

    • EcLTP (E. crus-galli lipid transfer protein; Plants)

    • Source

    • Echinochloa crusgalli L. (seeds of weed cereal barnyard grass)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • AISCGQVSSAIGPCLSYARGQGSAPSAGCC

    • Sequence Length

    • 30

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

      • Fungi: Phytophthora infestans (IC50=6 µM).

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00386 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00386.

Physicochemical Information

    • Formula

    • C113H185N35O40S4

    • Absent Amino Acids

    • DEFHKMNTW

    • Common Amino Acids

    • S

    • Mass

    • 2802.16

    • PI

    • 7.92

    • Basic Residues

    • 1

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 9

    • Net Charge

    • +1

    • Boman Index

    • -8.87

    • Hydrophobicity

    • 0.44

    • Aliphatic Index

    • 65.33

    • Half Life

      • Mammalian:4.4 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 1740

    • Absorbance 280nm

    • 60

    • Polar Residues

    • 16

DRAMP00386

DRAMP00386 chydropathy plot

Comments Information

    • Function

    • Possesses antifungal activity.

Literature Information

  • ·Literature 1

    • Title

    • Defense peptides from barnyard grass (Echinochloa crusgalli L.) seeds.

    • Reference

    • Peptides. 2012 Nov;38(1):33-40.

    • Author

    • Rogozhin EA, Ryazantsev DY, Grishin EV, Egorov TA, Zavriev SK.