• DRAMP ID

    • DRAMP00389
    • Peptide Name

    • EcAMP2.1 (truncated EcAMP2 without five C-terminal residues)
    • Source

    • Echinochloa crus-galli (Barnyard grass) (Panicum crus-galli)
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • DRCSQQCQHHRDPDRKQQCMRECRRH
    • Sequence Length

    • 26
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Antifungal
    • Target Organism

      • Fungi: Phytophthora infestans (IC50=24 µM).
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP00389 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP00389.
    • Formula

    • C127H210N56O41S5
    • Absent Amino Acids

    • AFGILNTVWY
    • Common Amino Acids

    • R
    • Mass

    • 3337.72
    • PI

    • 8.98
    • Basic Residues

    • 10
    • Acidic Residues

    • 4
    • Hydrophobic Residues

    • 0
    • Net Charge

    • +6
    • Boman Index

    • -165.65
    • Hydrophobicity

    • -2.404
    • Aliphatic Index

    • 0
    • Half Life

      • Mammalian:1.1 hour
      • Yeast:3 min
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 250
    • Absorbance 280nm

    • 10
    • Polar Residues

    • 5

DRAMP00389

DRAMP00389 chydropathy plot
    • Function

    • EcAMP2.1 inhibits spore germination of P. infestans with an IC50 of 24 µM but have no antibacterial activity.
    • PTM

    • Contains two disulfide bonds (By similarity).
  • ·Literature 1
    • Title

    • Defense peptides from barnyard grass (Echinochloa crusgalli L.) seeds.
    • Reference

    • Peptides. 2012 Nov;38(1):33-40.
    • Author

    • Rogozhin EA, Ryazantsev DY, Grishin EV, Egorov TA, Zavriev SK.