• DRAMP ID

    • DRAMP00406
    • Peptide Name

    • Defensin D5 (So-D5; Antimicrobial peptide D5; Plant defensin)
    • Source

    • Spinacia oleracea (Spinach)
    • Family

    • Belongs to the DEFL family
    • Gene

    • Not found
    • Sequence

    • MFFSSKKCKTVXKTFRGPCVRNAN
    • Sequence Length

    • 24
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
    • Target Organism

      • Gram-positive bacterium: Clavibacter michiganensis;
      • Gram-negative bacterium: Ralstonia solanacearum.
      • Fungi: Fusarium culmorum, Fusarium solani, Bipolaris maydis and Colletotrichum lagenarium.
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP00406 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP00406.
    • Formula

    • C116H187N35O29S3
    • Absent Amino Acids

    • DEHILQWY
    • Common Amino Acids

    • K
    • Mass

    • 2761.5
    • PI

    • 10.48
    • Basic Residues

    • 6
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 6
    • Net Charge

    • +6
    • Boman Index

    • -52.58
    • Hydrophobicity

    • -0.463
    • Aliphatic Index

    • 28.33
    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 125
    • Absorbance 280nm

    • 5.43
    • Polar Residues

    • 9

DRAMP00406

DRAMP00406 chydropathy plot
    • Function

    • Antimicrobial peptide. Active against Fusarium spp., Gram-positive and Gram-negative bacterial pathogens.
    • Tissue specificity

    • Distributed in the epidermal cell layer of leaves and in the subepidermal layer region of stems. Not in roots.
    • Developmental stage

    • Present throughout the life of the leaf.
  • ·Literature 1
    • Title

    • Novel defensin subfamily from spinach (Spinacia oleracea).
    • Reference

    • FEBS Lett. 1998; 435: 159-162.
    • Author

    • Segura A, Moreno M, Molina A, Garcia-Olmedo F.