• DRAMP ID

    • DRAMP00430
    • Peptide Name

    • Defensin-like protein 1 (Cp-thionin I; Cp-thionin-1; Gamma-thionin I; Plant defensin)
    • Source

    • Vigna unguiculata (Cowpea)
    • Family

    • Belongs to the DEFL family
    • Gene

    • Not found
    • Sequence

    • RVCESQSHGFKGACTGDHNCALVCRNEGFSGGNCRGFRRRCFCTLKC
    • Sequence Length

    • 47
    • Protein Existence

    • Protein level
    • Biological Activity

    • Not found
    • Target Organism

    • No MICs found in DRAMP database
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Bridge
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP00430 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP00430.
    • Formula

    • C210H333N75O63S8
    • Absent Amino Acids

    • IMPWY
    • Common Amino Acids

    • C
    • Mass

    • 5172.9
    • PI

    • 8.97
    • Basic Residues

    • 10
    • Acidic Residues

    • 3
    • Hydrophobic Residues

    • 10
    • Net Charge

    • +7
    • Boman Index

    • -122.8
    • Hydrophobicity

    • -0.457
    • Aliphatic Index

    • 33.19
    • Half Life

      • Mammalian:1 hour
      • Yeast:2 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 500
    • Absorbance 280nm

    • 10.87
    • Polar Residues

    • 23

DRAMP00430

DRAMP00430 chydropathy plot
    • Function

    • Inhibits trypsin but not chymotrypsin.
    • Subunit structure

    • Monomer and homodimer.
    • PTM

    • Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43 (By similarity).
  • ·Literature 1
    • Title

    • Inhibition of trypsin by cowpea thionin: characterization, molecular modeling, and docking.
    • Reference

    • Proteins. 2002 Aug 1;48(2):311-319.
    • Author

    • Melo FR, Rigden DJ, Franco OL, Mello LV, Ary MB, Grossi de S¡ MF, Bloch C Jr.