General Information

    • DRAMP ID

    • DRAMP00433

    • Peptide Name

    • Defensin-like protein 2 (Gamma-zeathionin-2; Plant defensin)

    • Source

    • Zea mays (Maize)

    • Family

    • Belongs to the DEFL family

    • Gene

    • Not found

    • Sequence

    • RVCMGKSQHHSFPCISDRLCSNECVKEDGGWTAGYCHLRYCRCQKAC

    • Sequence Length

    • 47

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Bridge

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00433 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00433.

Physicochemical Information

    • Formula

    • C222H346N72O66S9

    • Absent Amino Acids

    • ?

    • Common Amino Acids

    • C

    • Mass

    • 5368.17

    • PI

    • 8.51

    • Basic Residues

    • 10

    • Acidic Residues

    • 4

    • Hydrophobic Residues

    • 9

    • Net Charge

    • +6

    • Boman Index

    • -107.42

    • Hydrophobicity

    • -0.545

    • Aliphatic Index

    • 41.49

    • Half Life

      • Mammalian:1 hour
      • Yeast:2 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 8980

    • Absorbance 280nm

    • 195.22

    • Polar Residues

    • 20

DRAMP00433

DRAMP00433 chydropathy plot

Comments Information

    • Function

    • Sodium channel blocker.

    • PTM

    • Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43 (By similarity).

Literature Information

  • ·Literature 1

    • Title

    • Complete amino acid sequences of two gamma-thionins from maize (Zea mays L.) seeds.

    • Reference

    • Protein Pept. Lett. 1996;3:267-274.

    • Author

    • Castro M.S, Fontes W, Morhy L, Bloch C. Jr.