General Information
-
DRAMP ID
- DRAMP00438
-
Peptide Name
- Defensin-like protein 1 (Gamma-thionin 1; Plant defensin)
-
Source
- Nicotiana paniculata
-
Family
- Belongs to the DEFL family
-
Gene
- THIO1
-
Sequence
- KSTCKAESNTFPGLCITKPPCRKACLSEKFTDGKCSKILRRCICYKPCVFDGKMIQTGAENLAEEAETLAAALLEEEMMDN
-
Sequence Length
- 81
-
UniProt Entry
- O24115
-
Protein Existence
- Transcript level
Activity Information
-
Biological Activity
- Antimicrobial, Antifungal
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Bridge
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP00438.
Physicochemical Information
-
Formula
- C380H625N103O121S11
Absent Amino Acids
- HW
Common Amino Acids
- EKAC
Mass
- 8925.42
PI
- 6.44
Basic Residues
- 12
Acidic Residues
- 12
Hydrophobic Residues
- 23
Net Charge
- 0
-
Boman Index
- -134.15
Hydrophobicity
- -0.296
Aliphatic Index
- 66.42
Half Life
-
- Mammalian:1.3 hour
- Yeast:3 min
- E.coli:2 min
Extinction Coefficient Cystines
- 1990
Absorbance 280nm
- 24.88
Polar Residues
- 26
DRAMP00438
Comments Information
PTM
- Contains four disulfide bonds 4-48; 15-35; 21-42; 25-44.
Literature Information
- ·Literature 1
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Title
- A cDNA clone for gamma-thionin from Nicotiana paniculata.
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Pubmed ID
- PubMed ID is not available
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Reference
- Plant Gene Register PGR97-132.
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Author
- Komori T, Yamada S, Imaseki H.