General Information

    • DRAMP ID

    • DRAMP00439

    • Peptide Name

    • Defensin-like protein (Gamma-thionin homolog PPT; Plant defensin)

    • Source

    • Petunia integrifolia (Violet-flowered petunia)

    • Family

    • Belongs to the DEFL family

    • Gene

    • Not found

    • Sequence

    • RTCESQSHRFHGTCVRESNCASVCQTEGFIGGNCRAFRRRCFCTRNC

    • Sequence Length

    • 47

    • Protein Existence

    • Transcript level

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Bridge

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00439 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00439.

Physicochemical Information

    • Formula

    • C215H342N80O67S8

    • Absent Amino Acids

    • DKLMPWY

    • Common Amino Acids

    • CR

    • Mass

    • 5376.06

    • PI

    • 9.01

    • Basic Residues

    • 10

    • Acidic Residues

    • 3

    • Hydrophobic Residues

    • 9

    • Net Charge

    • +7

    • Boman Index

    • -161.45

    • Hydrophobicity

    • -0.645

    • Aliphatic Index

    • 24.89

    • Half Life

      • Mammalian:1 hour
      • Yeast:2 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 500

    • Absorbance 280nm

    • 10.87

    • Polar Residues

    • 23

DRAMP00439

DRAMP00439 chydropathy plot

Comments Information

    • Function

    • May be involved in the defense of the pistil against pathogen infection.

    • Tissue specificity

    • Predominantly expressed in the pistil during all stages of flower development.

    • PTM

    • Contains four disulfide bonds 3-47; 14-34; 20-21; 24-43 (By similarity).

Literature Information

  • ·Literature 1

    • Title

    • Characterization of a predominantly pistil-expressed gene encoding a gamma-thionin-like protein of Petunia inflata.

    • Reference

    • Plant Mol Biol. 1994 Oct;26(1):459-464.

    • Author

    • Karunanandaa B, Singh A, Kao TH.