General Information

    • DRAMP ID

    • DRAMP00440

    • Peptide Name

    • Defensin SD2 (Plant defensin)

    • Source

    • Helianthus annuus (Common sunflower)

    • Family

    • Belongs to the DEFL family

    • Gene

    • SD2

    • Sequence

    • NEMGGPLVVEARTCESQSHKFKGTCLSDTNCANVCHSERFSGGKCRGFRRRCFCTTHC

    • Sequence Length

    • 58

    • Protein Existence

    • Transcript level

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Bridge

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00440 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00440.

Physicochemical Information

    • Formula

    • C263H419N89O83S9

    • Absent Amino Acids

    • IWY

    • Common Amino Acids

    • C

    • Mass

    • 6444.31

    • PI

    • 8.75

    • Basic Residues

    • 12

    • Acidic Residues

    • 5

    • Hydrophobic Residues

    • 11

    • Net Charge

    • +7

    • Boman Index

    • -155.69

    • Hydrophobicity

    • -0.593

    • Aliphatic Index

    • 31.9

    • Half Life

      • Mammalian:1.4 hour
      • Yeast:3 min
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 500

    • Absorbance 280nm

    • 8.77

    • Polar Residues

    • 27

DRAMP00440

DRAMP00440 chydropathy plot

Comments Information

    • Function

    • May play a protective role in flowers by protecting the reproductive organs from potential pathogen attack.

    • Tissue specificity

    • Highest expression in flowers and to a lesser extent in leaves. Lower levels in hypocotyls. No expression in roots and cotyledons.

    • Developmental stage

    • Expressed progressively during flower development reaching the highest level in the mature fertilized flower stage.

    • PTM

    • Problely contains four disulfide bonds 14-57; 25-44; 31-52; 35-54.

Literature Information

  • ·Literature 1

    • Title

    • A defensin gene expressed in sunflower inflorescence.

    • Reference

    • Plant Physiol. Biochem. 2000;38:253-258.

    • Author

    • Urdangarin M.C, de la Canal L.