General Information
-
DRAMP ID
- DRAMP00448
-
Peptide Name
- Defensin Tk-AMP-D6.1 (Plant defensin)
-
Source
- Triticum kiharae (Wheat)
-
Family
- Belongs to the DEFL family
-
Gene
- Not found
-
Sequence
- RECRSQSKQFVGLCVSDTNCASVCLTEHFPGGKCDGYRRCFCTKDC
-
Sequence Length
- 46
-
UniProt Entry
- P84969
-
Protein Existence
- Protein level
Activity Information
-
Biological Activity
- Antimicrobial, Antifungal
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Bridge
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP00448.
Physicochemical Information
-
Formula
- C211H334N66O68S8
Absent Amino Acids
- IMW
Common Amino Acids
- C
Mass
- 5139.85
PI
- 8.21
Basic Residues
- 8
Acidic Residues
- 5
Hydrophobic Residues
- 9
Net Charge
- +3
-
Boman Index
- -113.23
Hydrophobicity
- -0.441
Aliphatic Index
- 38.04
Half Life
-
- Mammalian:1 hour
- Yeast:2 min
- E.coli:2 min
Extinction Coefficient Cystines
- 1990
Absorbance 280nm
- 44.22
Polar Residues
- 21
DRAMP00448
Comments Information
Function
- Plant defense peptide (By similarity).
PTM
- Contains four disulfide bonds 3-46; 14-34; 20-40; 24-42 (By similarity).
Literature Information
- ·Literature 1
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Title
- Seed defensins from T. kiharae and related species: genome localization of defensin-encoding genes.
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Pubmed ID
- 17321030
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Reference
- Biochimie. 2007 May;89(5):605-612.
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Author
- Odintsova TI, Egorov TA, Musolyamov AKh, Odintsova MS, Pukhalsky VA, Grishin EV.