General Information

    • DRAMP ID

    • DRAMP00453

    • Peptide Name

    • Defensin J1-2 (Plant defensin)

    • Source

    • Capsicum annuum (Bell pepper)

    • Family

    • Belongs to the DEFL family

    • Gene

    • Not found

    • Sequence

    • RTCESQSHRFKGLCFSKSNCGSVCHTEGFNGGHCRGFRRRCFCTRHC

    • Sequence Length

    • 47

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

      • Fungi: Fusarium oxysporum, Botrytis cinerea.

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Bridge

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00453 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00453.

Physicochemical Information

    • Formula

    • C220H341N81O63S8

    • Absent Amino Acids

    • ADIMPWY

    • Common Amino Acids

    • C

    • Mass

    • 5385.11

    • PI

    • 9.37

    • Basic Residues

    • 13

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 7

    • Net Charge

    • +11

    • Boman Index

    • -151.59

    • Hydrophobicity

    • -0.768

    • Aliphatic Index

    • 14.47

    • Half Life

      • Mammalian:1 hour
      • Yeast:2 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 500

    • Absorbance 280nm

    • 10.87

    • Polar Residues

    • 24

DRAMP00453

DRAMP00453 chydropathy plot

Comments Information

    • Tissue specificity

    • Expressed in flowers and in young fruits.

    • PTM

    • Contains four disulfide bonds 3-47; 14-34; 20-41; 24-43.

Literature Information

  • ·Literature 1

    • Title

    • Fruit-specific expression of a defensin-type gene family in bell pepper. Upregulation during ripening and upon wounding.

    • Reference

    • Plant Physiol. 1996 Oct;112(2):615-622.

    • Author

    • Meyer B, Houln© G, Pozueta-Romero J, Schantz ML, Schantz R.
  • ·Literature 2

    • Title

    • Alteration of the expression of a plant defensin gene by exon shuffling in bell pepper (Capsicum annuum L.).

    • Reference

    • Mol Gen Genet. 1998 Sep;259(5):504-510.

    • Author

    • Houln© G, Meyer B, Schantz R.