General Information

    • DRAMP ID

    • DRAMP00461

    • Peptide Name

    • Defensin-like protein 5 (Protein LCR66; Plant defensin 2.4; Plant defensin)

    • Source

    • Arabidopsis thaliana (Mouse-ear cress)

    • Family

    • Belongs to the DEFL family

    • Gene

    • PDF2.4

    • Sequence

    • RTCETSSNLFNGPCLSSSNCANVCHNEGFSDGDCRGFRRRCLCTRPC

    • Sequence Length

    • 47

    • Protein Existence

    • Homology

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Bridge

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00461 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00461.

Physicochemical Information

    • Formula

    • C205H326N72O70S8

    • Absent Amino Acids

    • IKMQWY

    • Common Amino Acids

    • C

    • Mass

    • 5175.76

    • PI

    • 8.23

    • Basic Residues

    • 7

    • Acidic Residues

    • 4

    • Hydrophobic Residues

    • 8

    • Net Charge

    • +3

    • Boman Index

    • -143

    • Hydrophobicity

    • -0.587

    • Aliphatic Index

    • 33.19

    • Half Life

      • Mammalian:1 hour
      • Yeast:2 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 500

    • Absorbance 280nm

    • 10.87

    • Polar Residues

    • 26

DRAMP00461

DRAMP00461 chydropathy plot

Comments Information

    • PTM

    • Contains four disulfide bonds 4-51; 15-36; 21-45; 25-47, and Pyrrolidone carboxylic acid at position 1.

Literature Information

  • ·Literature 1

    • Title

    • Simultaneous high-throughput recombinational cloning of open reading frames in closed and open configurations.

    • Reference

    • Plant Biotechnol J. 2006 May;4(3):317-324.

    • Author

    • Underwood BA, Vanderhaeghen R, Whitford R, Town CD, Hilson P.