General Information
-
DRAMP ID
- DRAMP00468
-
Peptide Name
- Putative defensin-like protein 12 (Plant defensin)
-
Source
- Arabidopsis thaliana (Mouse-ear cress)
-
Family
- Belongs to the DEFL family
-
Gene
- Not found
-
Sequence
- QMNDCDCDHDHRCGEWEDESHGNCKQHHLRVVCTCTLDCLDISSTSNA
-
Sequence Length
- 48
-
UniProt Entry
- Q2V477
-
Protein Existence
- Homology
Activity Information
-
Biological Activity
- Antimicrobial, Antifungal
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Bridge
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP00468.
Physicochemical Information
-
Formula
- C215H331N71O81S8
Absent Amino Acids
- FPY
Common Amino Acids
- CD
Mass
- 5462.9
PI
- 4.74
Basic Residues
- 8
Acidic Residues
- 10
Hydrophobic Residues
- 8
Net Charge
- -2
-
Boman Index
- -147.38
Hydrophobicity
- -0.894
Aliphatic Index
- 46.67
Half Life
-
- Mammalian:0.8 hour
- Yeast:10 min
- E.coli:>10 hour
Extinction Coefficient Cystines
- 5875
Absorbance 280nm
- 125
Polar Residues
- 19
DRAMP00468
Comments Information
Caution
- Lacks 1 of the 4 disulfide bonds, which are conserved features of the family.
Literature Information
- ·Literature 1
-
Title
- Genome organization of more than 300 defensin-like genes in Arabidopsis.
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Pubmed ID
- 15955924
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Reference
- Plant Physiol. 2005 Jun;138(2):600-610.
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Author
- Silverstein KA, Graham MA, Paape TD, VandenBosch KA.