General Information
-
DRAMP ID
- DRAMP00491
-
Peptide Name
- Defensin-like protein 35 (Plant defensin)
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Source
- Arabidopsis thaliana (Mouse-ear cress)
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Family
- Belongs to the DEFL family
-
Gene
- Not found
-
Sequence
- KSMNPTGRRCPDPNGVEKKSMCYSSCKTQGFMGGSCQGHKGNYMCECYEG
-
Sequence Length
- 50
-
Protein Existence
- Transcript level
Activity Information
-
Biological Activity
- Antimicrobial, Antifungal
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
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Structure
- Not found
-
Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP00491.
Physicochemical Information
-
Formula
- C222H348N68O74S10
Absent Amino Acids
- AILW
Common Amino Acids
- G
Mass
- 5474.22
PI
- 8.62
Basic Residues
- 8
Acidic Residues
- 4
Hydrophobic Residues
- 2
Net Charge
- +4
-
Boman Index
- -113.34
Hydrophobicity
- -1.018
Aliphatic Index
- 5.8
Half Life
-
- Mammalian:1.3 hour
- Yeast:3 min
- E.coli:2 min
Extinction Coefficient Cystines
- 4845
Absorbance 280nm
- 98.88
Polar Residues
- 27
DRAMP00491
Comments Information
Caution
- Lacks 1 of the 4 disulfide bonds, which are conserved features of the family.
Literature Information
- ·Literature 1
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Title
- Genome organization of more than 300 defensin-like genes in Arabidopsis.
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Pubmed ID
- 15955924
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Reference
- Plant Physiol. 2005 Jun;138(2):600-610.
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Author
- Silverstein KA, Graham MA, Paape TD, VandenBosch KA.