General Information
-
DRAMP ID
- DRAMP00493
-
Peptide Name
- Defensin-like protein 37 (Plant defensin)
-
Source
- Arabidopsis thaliana (Mouse-ear cress)
-
Family
- Belongs to the DEFL family
-
Gene
- EDA21
-
Sequence
- TTAGRRDGKSGRTEWLYVAGECAKLPRCNKYCVSNGFHLGGFCEKLSPQASYLSCVCKYT
-
Sequence Length
- 60
-
Protein Existence
- Homology
Activity Information
-
Biological Activity
- Antimicrobial, Antifungal
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP00493.
Physicochemical Information
-
Formula
- C287H447N83O85S6
Absent Amino Acids
- IM
Common Amino Acids
- GC
Mass
- 6612.57
PI
- 9.04
Basic Residues
- 10
Acidic Residues
- 4
Hydrophobic Residues
- 15
Net Charge
- +6
-
Boman Index
- -101.39
Hydrophobicity
- -0.412
Aliphatic Index
- 53.67
Half Life
-
- Mammalian:7.2 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 11835
Absorbance 280nm
- 200.59
Polar Residues
- 28
DRAMP00493
Comments Information
Caution
- Lacks 1 of the 4 disulfide bonds, which are conserved features of the family.
Literature Information
- ·Literature 1
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Title
- Genome organization of more than 300 defensin-like genes in Arabidopsis.
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Pubmed ID
- 15955924
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Reference
- Plant Physiol. 2005 Jun;138(2):600-610.
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Author
- Silverstein KA, Graham MA, Paape TD, VandenBosch KA.