General Information
-
DRAMP ID
- DRAMP00502
-
Peptide Name
- Defensin-like protein 46 (Plant defensin)
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Source
- Arabidopsis thaliana (Mouse-ear cress)
-
Family
- Belongs to the DEFL family
-
Gene
- Not found
-
Sequence
- IDAGIKGFDTDHCDTRCYGRDECMNYCIKAGFPKGGQCGSLCIPCGFKCCCQK
-
Sequence Length
- 53
-
Protein Existence
- Homology
Activity Information
-
Biological Activity
- Antimicrobial, Antifungal
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP00502.
Physicochemical Information
-
Formula
- C240H373N69O74S11
Absent Amino Acids
- VW
Common Amino Acids
- C
Mass
- 5761.68
PI
- 7.64
Basic Residues
- 8
Acidic Residues
- 6
Hydrophobic Residues
- 10
Net Charge
- +2
-
Boman Index
- -79.37
Hydrophobicity
- -0.259
Aliphatic Index
- 40.57
Half Life
-
- Mammalian:20 hour
- Yeast:30 min
- E.coli:>10 hour
Extinction Coefficient Cystines
- 3605
Absorbance 280nm
- 69.33
Polar Residues
- 24
DRAMP00502
Comments Information
Function
- May have antifungal activity.
PTM
- Contains four disulfide bonds (By similarity).
Literature Information
- ·Literature 1
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Title
- Genome organization of more than 300 defensin-like genes in Arabidopsis.
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Pubmed ID
- 15955924
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Reference
- Plant Physiol. 2005 Jun;138(2):600-610.
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Author
- Silverstein KA, Graham MA, Paape TD, VandenBosch KA.