General Information

    • DRAMP ID

    • DRAMP00506

    • Peptide Name

    • Defensin-like protein 50 (Protein LCR49; Plant defensin)

    • Source

    • Arabidopsis thaliana (Mouse-ear cress)

    • Family

    • Belongs to the DEFL family

    • Gene

    • LCR49

    • Sequence

    • SEIKAKINGLECFNTCTPYYDDYKCNVDCLSSGYPAGDCHIVSPSQPKKCCCY

    • Sequence Length

    • 53

    • Protein Existence

    • Homology

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00506 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00506.

Physicochemical Information

    • Formula

    • C252H382N64O82S8

    • Absent Amino Acids

    • MRW

    • Common Amino Acids

    • C

    • Mass

    • 5876.66

    • PI

    • 5.52

    • Basic Residues

    • 6

    • Acidic Residues

    • 6

    • Hydrophobic Residues

    • 10

    • Net Charge

    • 0

    • Boman Index

    • -76.87

    • Hydrophobicity

    • -0.402

    • Aliphatic Index

    • 51.51

    • Half Life

      • Mammalian:1.9 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 7950

    • Absorbance 280nm

    • 152.88

    • Polar Residues

    • 26

DRAMP00506

DRAMP00506 chydropathy plot

Comments Information

    • PTM

    • Contains four disulfide bonds (By similarity).

Literature Information

  • ·Literature 1

    • Title

    • Experimental validation of novel genes predicted in the un-annotated regions of the Arabidopsis genome.

    • Reference

    • BMC Genomics. 2007 Jan 17;8:18.

    • Author

    • Moskal WA Jr, Wu HC, Underwood BA, Wang W, Town CD, Xiao Y.
  • ·Literature 2

    • Title

    • Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.

    • Reference

    • Plant Mol Biol. 2001 May;46(1):17-34.

    • Author

    • Vanoosthuyse V, Miege C, Dumas C, Cock JM.
  • ·Literature 3

    • Title

    • Genome organization of more than 300 defensin-like genes in Arabidopsis.

    • Reference

    • Plant Physiol. 2005 Jun;138(2):600-610.

    • Author

    • Silverstein KA, Graham MA, Paape TD, VandenBosch KA.