General Information
-
DRAMP ID
- DRAMP00507
-
Peptide Name
- Defensin-like protein 51 (Protein LCR48; Plant defensin)
-
Source
- Arabidopsis thaliana (Mouse-ear cress)
-
Family
- Belongs to the DEFL family
-
Gene
- LCR48
-
Sequence
- SEIKAKINGLECFNTCTSYYDDHKCNVDCLSSGYPAGECYTVSPSQPKKCCCY
-
Sequence Length
- 53
-
Protein Existence
- Homology
Activity Information
-
Biological Activity
- Antimicrobial, Antifungal
-
Target Organism
- No MICs found in DRAMP database
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP00507.
Physicochemical Information
-
Formula
- C249H378N64O84S8
Absent Amino Acids
- MRW
Common Amino Acids
- C
Mass
- 5868.6
PI
- 5.56
Basic Residues
- 6
Acidic Residues
- 6
Hydrophobic Residues
- 9
Net Charge
- 0
-
Boman Index
- -85.85
Hydrophobicity
- -0.485
Aliphatic Index
- 44.15
Half Life
-
- Mammalian:1.9 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 7950
Absorbance 280nm
- 152.88
Polar Residues
- 28
DRAMP00507
Comments Information
PTM
- Contains four disulfide bonds (By similarity).
Literature Information
- ·Literature 1
-
Title
- Small cysteine-rich peptides resembling antimicrobial peptides have been under-predicted in plants.
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Pubmed ID
- 17565583
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Reference
- Plant J. 2007 Jul;51(2):262-280.
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Author
- Silverstein KA, Moskal WA Jr, Wu HC, Underwood BA, Graham MA, Town CD, VandenBosch KA.
- ·Literature 2
-
Title
- Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.
-
Pubmed ID
- 11437247
-
Reference
- Plant Mol Biol. 2001 May;46(1):17-34.
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Author
- Vanoosthuyse V, Miege C, Dumas C, Cock JM.
- ·Literature 3
-
Title
- Genome organization of more than 300 defensin-like genes in Arabidopsis.
-
Pubmed ID
- 15955924
-
Reference
- Plant Physiol. 2005 Jun;138(2):600-610.
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Author
- Silverstein KA, Graham MA, Paape TD, VandenBosch KA.