General Information
-
DRAMP ID
- DRAMP00520
-
Peptide Name
- Putative defensin-like protein 66 (Plant defensin)
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Source
- Arabidopsis thaliana (Mouse-ear cress)
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Family
- Belongs to the DEFL family
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Gene
- Not found
-
Sequence
- FSVQIGISVQAAPPTCGRDCTEKFLTQDCDKYCVGLSYKKGVCILSEGLPPKTSTYRCCCS
-
Sequence Length
- 61
-
UniProt Entry
- Q2V2Y6
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Protein Existence
- Homology
Activity Information
-
Biological Activity
- Antimicrobial, Antifungal
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
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Structure
- Not found
-
Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP00520.
Physicochemical Information
-
Formula
- C284H455N75O89S8
Absent Amino Acids
- HMNW
Common Amino Acids
- C
Mass
- 6600.67
PI
- 8.18
Basic Residues
- 7
Acidic Residues
- 5
Hydrophobic Residues
- 15
Net Charge
- +2
-
Boman Index
- -72.54
Hydrophobicity
- -0.039
Aliphatic Index
- 67.05
Half Life
-
- Mammalian:1.1 hour
- Yeast:3 min
- E.coli:2 min
Extinction Coefficient Cystines
- 4970
Absorbance 280nm
- 82.83
Polar Residues
- 27
DRAMP00520
Comments Information
Function
- May have antifungal activity.
PTM
- Contains four disulfide bonds (By similarity).
Literature Information
- ·Literature 1
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Title
- Genome organization of more than 300 defensin-like genes in Arabidopsis.
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Pubmed ID
- 15955924
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Reference
- Plant Physiol. 2005 Jun;138(2):600-610.
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Author
- Silverstein KA, Graham MA, Paape TD, VandenBosch KA.