General Information

    • DRAMP ID

    • DRAMP00558

    • Peptide Name

    • Defensin-like protein 109 (Plant defensin)

    • Source

    • Arabidopsis thaliana (Mouse-ear cress)

    • Family

    • Belongs to the DEFL family

    • Gene

    • Not found

    • Sequence

    • RPSFKPIPLFGEKLTQCFDTRPCLQGMLKCIEFCSSMGTADGQCNNENLCCCTHE

    • Sequence Length

    • 55

    • Protein Existence

    • Transcript level

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00558 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00558.

Physicochemical Information

    • Formula

    • C259H408N72O81S10

    • Absent Amino Acids

    • VWY

    • Common Amino Acids

    • C

    • Mass

    • 6147.12

    • PI

    • 5.61

    • Basic Residues

    • 6

    • Acidic Residues

    • 6

    • Hydrophobic Residues

    • 12

    • Net Charge

    • 0

    • Boman Index

    • -85.98

    • Hydrophobicity

    • -0.26

    • Aliphatic Index

    • 51.45

    • Half Life

      • Mammalian:1 hour
      • Yeast:2 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 500

    • Absorbance 280nm

    • 9.26

    • Polar Residues

    • 22

DRAMP00558

DRAMP00558 chydropathy plot

Comments Information

    • Function

    • Defense response to fungus.

    • PTM

    • Contains four disulfide bonds (By similarity).

Literature Information

  • ·Literature 1

    • Title

    • Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence features of the regions of 1,381,565 bp covered by twenty one physically assigned P1 and TAC clones.

    • Reference

    • DNA Res. 1998 Apr 30;5(2):131-145.

    • Author

    • Kaneko T, Kotani H, Nakamura Y, Sato S, Asamizu E, Miyajima N, Tabata S.
  • ·Literature 2

    • Title

    • Genome organization of more than 300 defensin-like genes in Arabidopsis.

    • Reference

    • Plant Physiol. 2005 Jun;138(2):600-610.

    • Author

    • Silverstein KA, Graham MA, Paape TD, VandenBosch KA.