General Information
-
DRAMP ID
- DRAMP00610
-
Peptide Name
- Putative defensin-like protein 165 (Protein LCR12; Plant defensin)
-
Source
- Arabidopsis thaliana (Mouse-ear cress)
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Family
- Belongs to the DEFL family
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Gene
- LCR12
-
Sequence
- QKRCRQELEPGKQCVLAKCRELCFKQLKGFGSCIEKPPGSSKYTCNCFYNCGPPGFF
-
Sequence Length
- 57
-
UniProt Entry
- P82727
-
Protein Existence
- Homology
Activity Information
-
Biological Activity
- Antimicrobial, Antifungal
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
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Structure
- Not found
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Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP00610.
Physicochemical Information
-
Formula
- C283H441N79O78S8
Absent Amino Acids
- DHMW
Common Amino Acids
- CK
Mass
- 6454.58
PI
- 9.03
Basic Residues
- 10
Acidic Residues
- 4
Hydrophobic Residues
- 12
Net Charge
- +6
-
Boman Index
- -98.11
Hydrophobicity
- -0.565
Aliphatic Index
- 41.05
Half Life
-
- Mammalian:0.8 hour
- Yeast:10 min
- E.coli:>10 hour
Extinction Coefficient Cystines
- 3480
Absorbance 280nm
- 62.14
Polar Residues
- 22
DRAMP00610
![DRAMP00610 chydropathy plot](http://dramp.cpu-bioinfor.org/tmp/all_info_png/pepwindow_DRAMP00610.1.png)
Comments Information
Function
- Defense response to fungus.
PTM
- Contains four disulfide bonds (By similarity).
Literature Information
- ·Literature 1
-
Title
- Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.
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Pubmed ID
- 11437247
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Reference
- Plant Mol Biol. 2001 May;46(1):17-34.
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Author
- Vanoosthuyse V, Miege C, Dumas C, Cock JM.
- ·Literature 2
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Title
- Genome organization of more than 300 defensin-like genes in Arabidopsis.
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Pubmed ID
- 15955924
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Reference
- Plant Physiol. 2005 Jun;138(2):600-610.
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Author
- Silverstein KA, Graham MA, Paape TD, VandenBosch KA.