General Information
-
DRAMP ID
- DRAMP00637
-
Peptide Name
- Defensin-like protein 197 (Trypsin inhibitor ATTI-6; Plant defensin)
-
Source
- Arabidopsis thaliana (Mouse-ear cress)
-
Family
- Belongs to the DEFL family
-
Gene
- ATTI6
-
Sequence
- KDDKFICVVEYGGDVGPTFCNPKFFPTLCRQNCRSFKGAKGGKCVKQPKHKHIKCFCDYCKDD
-
Sequence Length
- 63
-
Protein Existence
- Homology
Activity Information
-
Biological Activity
- Antimicrobial, Antifungal
-
Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
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Structure
- Not found
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Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP00637.
Physicochemical Information
-
Formula
- C317H488N88O87S8
Absent Amino Acids
- MW
Common Amino Acids
- K
Mass
- 7180.38
PI
- 8.98
Basic Residues
- 15
Acidic Residues
- 7
Hydrophobic Residues
- 14
Net Charge
- +8
-
Boman Index
- -126.03
Hydrophobicity
- -0.67
Aliphatic Index
- 38.57
Half Life
-
- Mammalian:1.3 hour
- Yeast:3 min
- E.coli:2 min
Extinction Coefficient Cystines
- 3480
Absorbance 280nm
- 56.13
Polar Residues
- 21
DRAMP00637
![DRAMP00637 chydropathy plot](http://dramp.cpu-bioinfor.org/tmp/all_info_png/pepwindow_DRAMP00637.1.png)
Comments Information
Function
- Defense response to fungus.
PTM
- Contains four disulfide bonds (By similarity).
Caution
- Was initially thought (PubMed
Literature Information
- ·Literature 1
-
Title
- Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.
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Pubmed ID
- 11437247
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Reference
- Plant Mol Biol. 2001 May;46(1):17-34.
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Author
- Vanoosthuyse V, Miege C, Dumas C, Cock JM.
- ·Literature 2
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Title
- Genome organization of more than 300 defensin-like genes in Arabidopsis.
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Pubmed ID
- 15955924
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Reference
- Plant Physiol. 2005 Jun;138(2):600-610.
-
Author
- Silverstein KA, Graham MA, Paape TD, VandenBosch KA.