General Information
-
DRAMP ID
- DRAMP00646
-
Peptide Name
- Defensin-like protein 208 (Plant defensin)
-
Source
- Arabidopsis thaliana (Mouse-ear cress)
-
Family
- Belongs to the DEFL family
-
Gene
- Not found
-
Sequence
- ACFKFLGECGAVPFPGTNADCTSCCVGNFGSAVCAGRVEVEGGVKHCHCYGTS
-
Sequence Length
- 53
-
UniProt Entry
- Q2V2Q8
-
Protein Existence
- Transcript level
Activity Information
-
Biological Activity
- Antimicrobial, Antifungal
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
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Structure
- Not found
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Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP00646.
Physicochemical Information
-
Formula
- C226H342N64O71S8
Absent Amino Acids
- IMQW
Common Amino Acids
- GC
Mass
- 5348.07
PI
- 6.03
Basic Residues
- 5
Acidic Residues
- 4
Hydrophobic Residues
- 16
Net Charge
- +1
-
Boman Index
- -26.99
Hydrophobicity
- 0.319
Aliphatic Index
- 49.62
Half Life
-
- Mammalian:4.4 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 1990
Absorbance 280nm
- 38.27
Polar Residues
- 26
DRAMP00646
![DRAMP00646 chydropathy plot](http://dramp.cpu-bioinfor.org/tmp/all_info_png/pepwindow_DRAMP00646.1.png)
Comments Information
Function
- Defense response to fungus.
PTM
- Contains three disulfide bonds (By similarity).
Caution
- Lacks 1 of the 4 disulfide bonds, which are conserved features of the family.
Literature Information
- ·Literature 1
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Title
- Genome organization of more than 300 defensin-like genes in Arabidopsis.
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Pubmed ID
- 15955924
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Reference
- Plant Physiol. 2005 Jun;138(2):600-610.
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Author
- Silverstein KA, Graham MA, Paape TD, VandenBosch KA.