General Information
-
DRAMP ID
- DRAMP00654
-
Peptide Name
- Defensin-like protein 216 (Plant defensin)
-
Source
- Arabidopsis thaliana (Mouse-ear cress)
-
Family
- Belongs to the DEFL family
-
Gene
- Not found
-
Sequence
- ILINESSDEQRIYSFSPTTSPFDPRSLNQELKIGRIGYCFDCARACMRRGKYIRTCSFERKLCRCSISDIK
-
Sequence Length
- 71
-
UniProt Entry
- P0CAY6
-
Protein Existence
- Homology
Activity Information
-
Biological Activity
- Antimicrobial, Antifungal
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
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Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP00654.
Physicochemical Information
-
Formula
- C356H574N106O107S7
Absent Amino Acids
- HVW
Common Amino Acids
- RSI
Mass
- 8275.54
PI
- 9.08
Basic Residues
- 13
Acidic Residues
- 8
Hydrophobic Residues
- 18
Net Charge
- +5
-
Boman Index
- -194.26
Hydrophobicity
- -0.485
Aliphatic Index
- 68.73
Half Life
-
- Mammalian:20 hour
- Yeast:30 min
- E.coli:>10 hour
Extinction Coefficient Cystines
- 4845
Absorbance 280nm
- 69.21
Polar Residues
- 26
DRAMP00654
![DRAMP00654 chydropathy plot](http://dramp.cpu-bioinfor.org/tmp/all_info_png/pepwindow_DRAMP00654.1.png)
Comments Information
Function
- Defense response to fungus.
PTM
- Contains three disulfide bonds (By similarity).
Caution
- Lacks 1 of the 4 disulfide bonds, which are conserved features of the family.
Literature Information
- ·Literature 1
-
Title
- Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.
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Pubmed ID
- 11437247
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Reference
- Plant Mol Biol. 2001 May;46(1):17-34.
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Author
- Vanoosthuyse V, Miege C, Dumas C, Cock JM.
- ·Literature 2
-
Title
- Genome organization of more than 300 defensin-like genes in Arabidopsis.
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Pubmed ID
- 15955924
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Reference
- Plant Physiol. 2005 Jun;138(2):600-610.
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Author
- Silverstein KA, Graham MA, Paape TD, VandenBosch KA.