General Information
-
DRAMP ID
- DRAMP00656
-
Peptide Name
- Defensin-like protein 218 (Plant defensin)
-
Source
- Arabidopsis thaliana (Mouse-ear cress)
-
Family
- Belongs to the DEFL family
-
Gene
- Not found
-
Sequence
- KNKKVVIIPGPKGERPDIKVVEGPSTVEDDFCYDCVRRCMVKGVGFYFRSCKGFVCRCYYPFMGGYGP
-
Sequence Length
- 68
-
UniProt Entry
- Q2V370
-
Protein Existence
- Transcript level
Activity Information
-
Biological Activity
- Antimicrobial, Antifungal
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
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Structure
- Not found
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Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP00656.
Physicochemical Information
-
Formula
- C346H531N91O92S8
Absent Amino Acids
- AHLQW
Common Amino Acids
- GV
Mass
- 7694.06
PI
- 8.99
Basic Residues
- 12
Acidic Residues
- 7
Hydrophobic Residues
- 17
Net Charge
- +5
-
Boman Index
- -98.61
Hydrophobicity
- -0.231
Aliphatic Index
- 55.59
Half Life
-
- Mammalian:1.3 hour
- Yeast:3 min
- E.coli:2 min
Extinction Coefficient Cystines
- 7825
Absorbance 280nm
- 116.79
Polar Residues
- 24
DRAMP00656
![DRAMP00656 chydropathy plot](http://dramp.cpu-bioinfor.org/tmp/all_info_png/pepwindow_DRAMP00656.1.png)
Comments Information
Function
- Defense response to fungus.
PTM
- Contains three disulfide bonds (By similarity).
Caution
- Lacks 1 of the 4 disulfide bonds, which are conserved features of the family.
Literature Information
- ·Literature 1
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Title
- Genome organization of more than 300 defensin-like genes in Arabidopsis.
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Pubmed ID
- 15955924
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Reference
- Plant Physiol. 2005 Jun;138(2):600-610.
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Author
- Silverstein KA, Graham MA, Paape TD, VandenBosch KA.