General Information
-
DRAMP ID
- DRAMP00659
-
Peptide Name
- Putative defensin-like protein 221 (Plant defensin)
-
Source
- Arabidopsis thaliana (Mouse-ear cress)
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Family
- Belongs to the DEFL family
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Gene
- Not found
-
Sequence
- NIMTKSILEGKTQFSIPSLSSTIDPAYEHIGHFPDDMKIIFCQQCAFHCIEKKKNIPHCENSICRCTLENIL
-
Sequence Length
- 72
-
UniProt Entry
- Q2V306
-
Protein Existence
- Homology
Activity Information
-
Biological Activity
- Antimicrobial, Antifungal
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
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Structure
- Not found
-
Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
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Predicted Structure
- There is no predicted structure for DRAMP00659.
Physicochemical Information
-
Formula
- C361H572N96O107S8
Absent Amino Acids
- VW
Common Amino Acids
- I
Mass
- 8225.57
PI
- 6.44
Basic Residues
- 11
Acidic Residues
- 8
Hydrophobic Residues
- 21
Net Charge
- +3
-
Boman Index
- -97.47
Hydrophobicity
- -0.153
Aliphatic Index
- 84.03
Half Life
-
- Mammalian:1.4 hour
- Yeast:3 min
- E.coli:>10 hour
Extinction Coefficient Cystines
- 1865
Absorbance 280nm
- 26.27
Polar Residues
- 23
DRAMP00659
Comments Information
Function
- Defense response to fungus.
PTM
- Contains three disulfide bonds (By similarity).
Caution
- Lacks 1 of the 4 disulfide bonds, which are conserved features of the family.
Literature Information
- ·Literature 1
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Title
- Genome organization of more than 300 defensin-like genes in Arabidopsis.
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Pubmed ID
- 15955924
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Reference
- Plant Physiol. 2005 Jun;138(2):600-610.
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Author
- Silverstein KA, Graham MA, Paape TD, VandenBosch KA.