General Information
-
DRAMP ID
- DRAMP00664
-
Peptide Name
- Putative defensin-like protein 227 (Protein SCRL28; SCR-like protein 28; Plant defensin)
-
Source
- Arabidopsis thaliana (Mouse-ear cress)
-
Family
- Belongs to the DEFL family
-
Gene
- SCRL28
-
Sequence
- IHVEQAGVCEFTGEFPGKCGNNGRKMCVEAMNKKNKGSPGENKKNLRCECFDNPVVILGRPKRICRCRNNC
-
Sequence Length
- 71
-
UniProt Entry
- P82647
-
Protein Existence
- Homology
Activity Information
-
Biological Activity
- Antimicrobial, Antifungal
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Target Organism
- No MICs found in DRAMP database
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Not found
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP00664.
Physicochemical Information
-
Formula
- C330H545N109O98S10
Absent Amino Acids
- WY
Common Amino Acids
- NCGK
Mass
- 7928.23
PI
- 9.2
Basic Residues
- 15
Acidic Residues
- 7
Hydrophobic Residues
- 15
Net Charge
- +8
-
Boman Index
- -179.61
Hydrophobicity
- -0.762
Aliphatic Index
- 50.7
Half Life
-
- Mammalian:20 hour
- Yeast:30 min
- E.coli:>10 hour
Extinction Coefficient Cystines
- 500
Absorbance 280nm
- 7.14
Polar Residues
- 27
DRAMP00664
Comments Information
Function
- May have antifungal activity.
PTM
- Contains four disulfide bonds (By similarity).
Literature Information
- ·Literature 1
-
Title
- Genome organization of more than 300 defensin-like genes in Arabidopsis.
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Pubmed ID
- 15955924
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Reference
- Plant Physiol. 2005 Jun;138(2):600-610.
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Author
- Silverstein KA, Graham MA, Paape TD, VandenBosch KA.