General Information
-
DRAMP ID
- DRAMP00692
-
Peptide Name
- Putative defensin-like protein 256 (Plant defensin)
-
Source
- Arabidopsis thaliana (Mouse-ear cress)
-
Family
- Belongs to the DEFL family
-
Gene
- Not found
-
Sequence
- VADYCNRDADCKRVCLRPYACNLTRHLCMCHPNDVSSSKQHCIPEHKGFGEGGPPPQRLKLYR
-
Sequence Length
- 63
-
UniProt Entry
- Q2V483
-
Protein Existence
- Homology
Activity Information
-
Biological Activity
- Antimicrobial, Antifungal
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
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N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
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Stereochemistry
- Not included yet
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Structure
- Not found
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Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP00692.
Physicochemical Information
-
Formula
- C305H482N98O88S8
Absent Amino Acids
- W
Common Amino Acids
- CPR
Mass
- 7186.27
PI
- 8.78
Basic Residues
- 14
Acidic Residues
- 6
Hydrophobic Residues
- 13
Net Charge
- +8
-
Boman Index
- -157.93
Hydrophobicity
- -0.768
Aliphatic Index
- 55.71
Half Life
-
- Mammalian:100 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 4845
Absorbance 280nm
- 78.15
Polar Residues
- 21
DRAMP00692
![DRAMP00692 chydropathy plot](http://dramp.cpu-bioinfor.org/tmp/all_info_png/pepwindow_DRAMP00692.1.png)
Comments Information
Function
- May have antifungal activity.
PTM
- Contains three disulfide bonds (By similarity).
Caution
- Lacks 1 of the 4 disulfide bonds, which are conserved features of the family.
Literature Information
- ·Literature 1
-
Title
- Two large Arabidopsis thaliana gene families are homologous to the Brassica gene superfamily that encodes pollen coat proteins and the male component of the self-incompatibility response.
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Pubmed ID
- 11437247
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Reference
- Plant Mol Biol. 2001 May;46(1):17-34.
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Author
- Vanoosthuyse V, Miege C, Dumas C, Cock JM.
- ·Literature 2
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Title
- Genome organization of more than 300 defensin-like genes in Arabidopsis.
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Pubmed ID
- 15955924
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Reference
- Plant Physiol. 2005 Jun;138(2):600-610.
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Author
- Silverstein KA, Graham MA, Paape TD, VandenBosch KA.