General Information
-
DRAMP ID
- DRAMP00762
-
Peptide Name
- Vaby D (Plant defensin)
-
Source
- Viola abyssinica (Ethiopian highlands)
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- GLPVCGETCFGGTCNTPGCTCDPWPVCTRN
-
Sequence Length
- 30
-
UniProt Entry
- No entry found
-
Protein Existence
- Not found
Activity Information
-
Biological Activity
- Antimicrobial, Antibacterial, Antifungal, Antiviral
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Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
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Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Bridge
-
Structure Description
- Not found
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Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP00762.
Physicochemical Information
-
Formula
- C127H194N36O42S6
Absent Amino Acids
- AHIKMQSY
Common Amino Acids
- C
Mass
- 3089.51
PI
- 4.37
Basic Residues
- 1
Acidic Residues
- 2
Hydrophobic Residues
- 5
Net Charge
- -1
-
Boman Index
- -25.89
Hydrophobicity
- -0.043
Aliphatic Index
- 32.33
Half Life
-
- Mammalian:30 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 5875
Absorbance 280nm
- 202.59
Polar Residues
- 18
DRAMP00762
Comments Information
PTM
- Contains three disulfide bonds
Literature Information
- ·Literature 1
-
Title
- Cyclotides from an extreme habitat: characterization of cyclic peptides from Viola abyssinica of the Ethiopian highlands.
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Pubmed ID
- 21434649
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Reference
- J Nat Prod. 2011 Apr 25;74(4):727-731.
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Author
- Yeshak MY, Burman R, Asres K, Göransson U.