General Information

    • DRAMP ID

    • DRAMP00793

    • Peptide Name

    • Vodo peptide M (Plant defensin)

    • Source

    • Viola odorata (Sweet violet)

    • Family

    • Belongs to the cyclotide family

    • Gene

    • Not found

    • Sequence

    • GAPICGESCFTGKCYTVQCSCSWPVCTRN

    • Sequence Length

    • 29

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Not found

    • Target Organism

    • No MICs found in DRAMP database

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Forms a head-to-tail cyclic backbone and that six cysteine residues are involved in three disulphide bonds.

    • Helical Wheel Diagram

    • DRAMP00793 helical wheel diagram

    • Predicted Structure

    • There is no predicted structure for DRAMP00793.

Physicochemical Information

    • Formula

    • C129H198N36O41S6

    • Absent Amino Acids

    • DHLM

    • Common Amino Acids

    • C

    • Mass

    • 3101.57

    • PI

    • 7.77

    • Basic Residues

    • 2

    • Acidic Residues

    • 1

    • Hydrophobic Residues

    • 6

    • Net Charge

    • +1

    • Boman Index

    • -26.89

    • Hydrophobicity

    • 0.086

    • Aliphatic Index

    • 36.9

    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 7365

    • Absorbance 280nm

    • 263.04

    • Polar Residues

    • 17

DRAMP00793

DRAMP00793 chydropathy plot

Comments Information

    • Function

    • Probably participates in a plant defense mechanism.

    • PTM

    • Problely contains three disulfide bonds 5-19; 9-21; 14-26.

Literature Information

  • ·Literature 1

    • Title

    • Primary and 3-D modelled structures of two cyclotides from Viola odorata.

    • Reference

    • Phytochemistry. 2003 Sep;64(1):135-142.

    • Author

    • Svang¥rd E, Göransson , Smith D, Verma C, Backlund A, Bohlin L, Claeson P.