• DRAMP ID

    • DRAMP00826
    • Peptide Name

    • Cycloviolacin-O23 (Plant defensin)
    • Source

    • Viola odorata (Sweet violet)
    • Family

    • Belongs to the cyclotide family
    • Gene

    • Not found
    • Sequence

    • GLPTCGETCFGGTCNTPGCTCDSSWPICTHN
    • Sequence Length

    • 31
    • Protein Existence

    • Protein level
    • Biological Activity

    • Insecticidal
    • Target Organism

    • No MICs found in DRAMP database
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

    • No cytotoxicity information found in the reference(s) presented
    • Binding Target

    • Not found
    • Serum or Protease Type

    • Not available
    • Stability Data

    • Not available
    • Assay

    • Not available
    • Linear/Cyclic

    • Cyclic
    • N-terminal Modification

    • No specific N-terminal
    • C-terminal Modification

    • No specific C-terminal
    • Nonterminal Modifications and Unusual Amino Acids

    • Disulfide bonds between Cys5 and Cys19; Cys9 and Cys21; Cys14 and Cys26.
    • Stereochemistry

    • L
    • Structure

    • Bridge
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP00826 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP00826.
    • Formula

    • C128H192N36O46S6
    • Absent Amino Acids

    • AKMQRVY
    • Common Amino Acids

    • CT
    • Mass

    • 3163.51
    • PI

    • 4.35
    • Basic Residues

    • 1
    • Acidic Residues

    • 2
    • Hydrophobic Residues

    • 4
    • Net Charge

    • -1
    • Boman Index

    • -28.16
    • Hydrophobicity

    • -0.148
    • Aliphatic Index

    • 25.16
    • Half Life

      • Mammalian:30 hour
      • Yeast:>20 hour
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 5875
    • Absorbance 280nm

    • 195.83
    • Polar Residues

    • 21

DRAMP00826

DRAMP00826 chydropathy plot
    • Function

    • Probably participates in a plant defense mechanism.
    • PTM

    • This is a cyclic peptide which may contain three disulfide bonds 5-19; 9-21; 14-26.
  • ·Literature 1
    • Title

    • A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability.
    • Reference

    • Biochem J. 2006 Nov 15;400(1):1-12.
    • Author

    • Ireland DC, Colgrave ML, Craik DJ.