General Information
-
DRAMP ID
- DRAMP00839
-
Peptide Name
- Cyclotide cter-A (Plant defensin)
-
Source
- Clitoria ternatea (Butterfly pea)
-
Family
- Belongs to the cyclotide family
-
Gene
- Not found
-
Sequence
- GVIPCGESCVFIPCISTVIGCSCKNKVCYRN
-
Sequence Length
- 31
-
UniProt Entry
- P86841
-
Protein Existence
- Protein level
Activity Information
-
Biological Activity
- Not found
-
Target Organism
- No MICs found in DRAMP database
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Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
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Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
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C-terminal Modification
- Not included yet
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Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
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Structure
- Bridge
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP00839.
Physicochemical Information
-
Formula
- C140H230N38O41S6
Absent Amino Acids
- ADHLMQW
Common Amino Acids
- C
Mass
- 3293.96
PI
- 8.33
Basic Residues
- 3
Acidic Residues
- 1
Hydrophobic Residues
- 9
Net Charge
- +2
-
Boman Index
- -9.7
Hydrophobicity
- 0.677
Aliphatic Index
- 87.74
Half Life
-
- Mammalian:30 hour
- Yeast:>20 hour
- E.coli:>10 hour
Extinction Coefficient Cystines
- 1865
Absorbance 280nm
- 62.17
Polar Residues
- 16
DRAMP00839
Comments Information
Function
- Probably participates in a plant defense mechanism.
PTM
- This is a cyclic peptide which may contain three disulfide bonds 5-21; 9-23; 14-28.
Literature Information
- ·Literature 1
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Title
- Discovery of cyclotides in the fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins.
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Pubmed ID
- 21194241
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Reference
- ACS Chem Biol. 2011 Apr 15;6(4):345-355.
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Author
- Poth AG, Colgrave ML, Philip R, Kerenga B, Daly NL, Anderson MA, Craik DJ.