General Information

    • DRAMP ID

    • DRAMP00934

    • Peptide Name

    • Vv-AMP1 (Vitis vinifera antimicrobial peptide 1; Plant defensin)

    • Source

    • Vitis vinifera (Berry)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • RTCESQSHRFKGTCVRQSNCAAVCQTEGFHGGNCRGFRRRCFCTKHC

    • Sequence Length

    • 47

    • UniProt Entry

    • No entry found

    • Protein Existence

    • Not found

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

      • Fungi: Fusarium oxysporum and Verticillium dahliae.

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP00934 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP00934.

Physicochemical Information

    • Formula

    • C216H343N81O64S8

    • Absent Amino Acids

    • DILMPWY

    • Common Amino Acids

    • C

    • Mass

    • 5355.08

    • PI

    • 9.37

    • Basic Residues

    • 12

    • Acidic Residues

    • 2

    • Hydrophobic Residues

    • 8

    • Net Charge

    • +10

    • Boman Index

    • -154.96

    • Hydrophobicity

    • -0.796

    • Aliphatic Index

    • 16.6

    • Half Life

      • Mammalian:1 hour
      • Yeast:2 min
      • E.coli:2 min

    • Extinction Coefficient Cystines

    • 500

    • Absorbance 280nm

    • 10.87

    • Polar Residues

    • 22

DRAMP00934

DRAMP00934 chydropathy plot

Comments Information

    • MOA

    • the inhibitory activity of Vv-AMP1 might be associated with altering the membrane permeability of the fungal membranes.

Literature Information

  • ·Literature 1

    • Title

    • Vv-AMP1, a ripening induced peptide from Vitis vinifera shows strong antifungal activity.

    • Reference

    • BMC Plant Biol. 2008 Jul 8;8:75.

    • Author

    • de Beer A, Vivier MA.