General Information
-
DRAMP ID
- DRAMP00975
-
Peptide Name
- SI alpha-2 (SIa2; Plant defensin)
-
Source
- Sorghum bicolor (Seeds)
-
Family
- Not found
-
Gene
- Not found
-
Sequence
- RVCMKGSAGFKGLCMRDQNCAQVCLQEGWGGGNCDGVMRQCKCIRQC
-
Sequence Length
- 47
-
UniProt Entry
- No entry found
-
Protein Existence
- Not found
Activity Information
-
Biological Activity
- Antimicrobial, Antifungal
-
Target Organism
- No MICs found in DRAMP database
-
Hemolytic Activity
-
- No hemolysis information or data found in the reference(s) presented in this entry
-
Cytotoxicity
-
- Not included yet
-
Binding Target
- Not found
Structure Information
-
Linear/Cyclic
- Not included yet
-
N-terminal Modification
- Not included yet
-
C-terminal Modification
- Not included yet
-
Nonterminal Modifications and Unusual Amino Acids
- Not included yet
-
Stereochemistry
- Not included yet
-
Structure
- Bridge
-
Structure Description
- Not found
-
Helical Wheel Diagram
-
PDB ID
- None
-
Predicted Structure
- There is no predicted structure for DRAMP00975.
Physicochemical Information
-
Formula
- C205H340N70O62S11
Absent Amino Acids
- HPTY
Common Amino Acids
- CG
Mass
- 5130.05
PI
- 8.75
Basic Residues
- 7
Acidic Residues
- 3
Hydrophobic Residues
- 10
Net Charge
- +4
-
Boman Index
- -84.34
Hydrophobicity
- -0.272
Aliphatic Index
- 47.66
Half Life
-
- Mammalian:1 hour
- Yeast:2 min
- E.coli:2 min
Extinction Coefficient Cystines
- 6000
Absorbance 280nm
- 130.43
Polar Residues
- 19
DRAMP00975
![DRAMP00975 chydropathy plot](http://dramp.cpu-bioinfor.org/tmp/all_info_png/pepwindow_DRAMP00975.1.png)
Comments Information
Comment
- No comments found on DRAMP database
Literature Information
- ·Literature 1
-
Title
- A new family of small (5 kDa) protein inhibitors of insect alpha-amylases from seeds or sorghum (Sorghum bicolar (L) Moench) have sequence homologies with wheat gamma-purothionins.
-
Pubmed ID
- 1995329
-
Reference
- FEBS Lett. 1991 Feb 11;279(1):101-104.
-
Author
- Bloch C Jr, Richardson M.