• • DRAMP ID

  • DRAMP00993

• • Peptide Name

  • WjAMP-1 (C-terminal domain of hevein; Plant defensin)

• • Source

  • Wasabia japonica L. (Wasabi plant) (Wasabia japonica)

• • Family

  • Not found

• • Gene

  • WjAMP-1

• • Sequence

  • QAGGQTCPGGICCSQWGYCGTTADYCSPNNNCQSNCWASG

• • Sequence Length

  • 40

• • UniProt Entry

  • No entry found

• • Protein Existence

  • Not found

• • Biological Activity

  • Antimicrobial, Antibacterial, Anti-Gram-, Antifungal

• • Target Organism

  • • Gram-negative bacteria: Escherichia coli (IC50=27.5 µg/ml), Pseudomonas cichorii (IC50=13.8 µg/ml), Pseudomonas glumae (IC50=20 µg/ml), Pseudomonas plantarii (IC50=22.5 µg/ml), Agrobacterium tumefaciens (IC50=12.5 µg/ml).
    • Fungi: Alternaria alternata (IC50=5.8 µg/ml), Botrytis cinerea (IC50=15 µg/ml), Fusarium solani (IC50=8.4 µg/ml), Magnaporte grisea (IC50=80 µg/ml).

• • Hemolytic Activity

  • • No hemolysis information or data found in the reference(s) presented in this entry

• • Cytotoxicity

  • • Not included yet

• • Binding Target

  • Chitin-binding

• • Linear/Cyclic

  • Not included yet

• • N-terminal Modification

  • Not included yet

• • C-terminal Modification

  • Not included yet

• • Nonterminal Modifications and Unusual Amino Acids

  • Not included yet

• • Stereochemistry

  • Not included yet

• • Structure

  • Not found

• • Structure Description

  • Not found

• • Helical Wheel Diagram

  • 

• • PDB ID

  • None

• Predicted Structure

• There is no predicted structure for DRAMP00993.

DRAMP00993

• • Function

  • WjAMP-1 showed antimicrobial activity against both fungi and bacteria.

• ·Literature 1

• • Title

  • C-terminal domain of a hevein-like protein from Wasabia japonica has potent antimicrobial activity.

• • Pubmed ID

  • 12668776

• • Reference

  • Plant Cell Physiol. 2003 Mar;44(3):296-303.

• • Author

  • Kiba A, Saitoh H, Nishihara M, Omiya K, Yamamura S.