• DRAMP ID

    • DRAMP00995
    • Peptide Name

    • IB-AMP2 (IBAMP2; Basic peptide AMP2; Plants)
    • Source

    • Impatiens balsamina (Balsam)
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • QYGRRCCNWGPGRRYCKRWC
    • Sequence Length

    • 20
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Antifungal
    • Target Organism

      • Fungi: Alternaria longipes (IC50=12 µg/ml), Botrytis cinerea (IC50=25 µg/ml), Cladosporium sphaerospermum (IC50=6 µg/ml), Fusarium culmorum (IC50=6 µg/ml), Penicillium digitatum (IC50=6 µg/ml), Trichoderma viride (IC50=12 µg/ml), Verticillium alboatrum (IC50=12 µg/ml).
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Bridge
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP00995 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP00995.
    • Formula

    • C108H162N40O25S4
    • Absent Amino Acids

    • ADEFHILMSTV
    • Common Amino Acids

    • R
    • Mass

    • 2548.97
    • PI

    • 9.93
    • Basic Residues

    • 6
    • Acidic Residues

    • 0
    • Hydrophobic Residues

    • 2
    • Net Charge

    • +6
    • Boman Index

    • -80.01
    • Hydrophobicity

    • -1.53
    • Aliphatic Index

    • 0
    • Half Life

      • Mammalian:0.8 hour
      • Yeast:10 min
      • E.coli:>10 hour
    • Extinction Coefficient Cystines

    • 14230
    • Absorbance 280nm

    • 748.95
    • Polar Residues

    • 10

DRAMP00995

DRAMP00995 chydropathy plot
    • Developmental stage

    • Highly expressed in dry mature seed and by the stages 2-5 of developing seed.
    • PTM

    • Contains two disulfide bonds C6-C16; C7-C20 and Pyrrolidone carboxylic acid at position 1 (Probable).
  • ·Literature 1
    • Title

    • A novel family of small cysteine-rich antimicrobial peptides from seed of Impatiens balsamina is derived from a single precursor protein.
    • Reference

    • J Biol Chem. 1997 Sep 26;272(39):24480-24487.
    • Author

    • Tailor RH, Acland DP, Attenborough S, Cammue BP, Evans IJ, Osborn RW, Ray JA, Rees SB, Broekaert WF.