• DRAMP ID

    • DRAMP01002
    • Peptide Name

    • Alpha-benincasin (Plants)
    • Source

    • Benincasa hispida
    • Family

    • Not found
    • Gene

    • Not found
    • Sequence

    • RDWERREFERRQNELRREQEQRREELL
    • Sequence Length

    • 27
    • Protein Existence

    • Protein level
    • Biological Activity

    • Antimicrobial, Antifungal
    • Target Organism

      • Fungi: Coprinus comatus, Pseudocercospora piricola.
    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry
    • Cytotoxicity

      • Not included yet
    • Binding Target

    • Not found
    • Linear/Cyclic

    • Not included yet
    • N-terminal Modification

    • Not included yet
    • C-terminal Modification

    • Not included yet
    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet
    • Stereochemistry

    • Not included yet
    • Structure

    • Not found
    • Structure Description

    • Not found
    • Helical Wheel Diagram

    • DRAMP01002 helical wheel diagram
    • PDB ID

    • None
    • Predicted Structure

    • There is no predicted structure for DRAMP01002.
    • Formula

    • C155H253N59O50
    • Absent Amino Acids

    • ACGHIKMPSTVY
    • Common Amino Acids

    • R
    • Mass

    • 3743.08
    • PI

    • 6.46
    • Basic Residues

    • 9
    • Acidic Residues

    • 9
    • Hydrophobic Residues

    • 5
    • Net Charge

    • 0
    • Boman Index

    • -200.67
    • Hydrophobicity

    • -2.693
    • Aliphatic Index

    • 43.33
    • Half Life

      • Mammalian:1 hour
      • Yeast:2 min
      • E.coli:2 min
    • Extinction Coefficient Cystines

    • 5500
    • Absorbance 280nm

    • 211.54
    • Polar Residues

    • 1

DRAMP01002

DRAMP01002 chydropathy plot
    • Function

    • Has weak antifungal activity toward C. comatus and P. piricola but not toward M. arachidicola. Inhibits cell-free translation in rabbit reticulocyte lysate system.
    • Miscellaneous

    • IC50 of 20 pM in rabbit reticulocyte.
  • ·Literature 1
    • Title

    • Purification and characterization of alpha- and beta-benincasins, arginine/glutamate-rich peptides with translation-inhibiting activity from wax gourd seeds.
    • Reference

    • Peptides. 2003 Jan;24(1):11-16.
    • Author

    • Ng TB, Parkash A, Tso WW.