• DRAMP ID

    • DRAMP01004
    • Peptide Name

    • Cucurmoschin (Plants)
    • Source

    • Cucurbita maxima (winter squash)
    • Family

    • Unknown
    • Gene

    • Unknown
    • Sequence

    • PQRGEGGRAGNLLREEQEI
    • Sequence Length

    • 19
    • Evidence code

    • Protein level
    • Biological Activity

    • Antifungal, Antimicrobial
    • Target Organism

      • Fungi: Botrytis cinerea (MIC=375 µM), Fusarium oxysporum (MIC=375 µM), Mycosphaerella arachidicola (MIC=375 µM).
    • Hemolytic activity

    • Unknown
    • Binding Target

    • Unknown
    • Structure

    • Unknown
    • Structure Description

    • Unknown
    • DRAMP01004 helical wheel diagram
    • Formula

    • C86H145N31O31
    • Absent Amino Acids

    • CDFHKMSTVWY
    • Common Amino Acids

    • EG
    • Mass

    • 2430.53
    • PI

    • 4.63
    • Basic Residues

    • 3
    • Acidic Residues

    • 4
    • Hydrophobic Residues

    • 4
    • Boman Index

    • -69.39
    • Hydrophobicity

    • -143.68
    • Aliphatic Index

    • 66.84
    • Half Life

      • Mammalian:>20 hour
      • Yeast:>20 hour
      • E.coli:?
    • Extinction Coefficient Cystines

    • 0
    • Absorbance 280nm

    • 0
    • Polar Residues

    • 5

DRAMP01004

DRAMP01004 chydropathy plot
    • Function

    • Has antifungal activity. Inhibits cell-free translation in rabbit reticulocyte lysate system.
  • Literature 1
    • Reference

    • Peptides. 2003 Jul;24(7):969-972.
    • Author

    • Wang HX, Ng TB.
    • Title

    • Isolation of cucurmoschin, a novel antifungal peptide abundant in arginine, glutamate and glycine residues from black pumpkin seeds.