General Information

    • DRAMP ID

    • DRAMP01053

    • Peptide Name

    • Thaumatin-like protein (CdTLP; Plants)

    • Source

    • Cassia didymobotrya (Popcorn cassia)

    • Family

    • Not found

    • Gene

    • Not found

    • Sequence

    • ATITFTNKCTRTVWPGG

    • Sequence Length

    • 17

    • Protein Existence

    • Protein level

Activity Information

    • Biological Activity

    • Antimicrobial, Antifungal

    • Target Organism

      • Fungi: Candida albicans 586 (EC50=6.2 µM), Candida parapsilosis ATCC 22019 (EC50=2.2 µM), Candida krusei ATCC 14243 (EC50=2.5 µM), C. krusei 80 (EC50=5.4 µM).

    • Hemolytic Activity

      • No hemolysis information or data found in the reference(s) presented in this entry

    • Cytotoxicity

      • Not included yet

    • Binding Target

    • Not found

Structure Information

    • Linear/Cyclic

    • Not included yet

    • N-terminal Modification

    • Not included yet

    • C-terminal Modification

    • Not included yet

    • Nonterminal Modifications and Unusual Amino Acids

    • Not included yet

    • Stereochemistry

    • Not included yet

    • Structure

    • Not found

    • Structure Description

    • Not found

    • Helical Wheel Diagram

    • DRAMP01053 helical wheel diagram

    • PDB ID

    • None

    • Predicted Structure

    • There is no predicted structure for DRAMP01053.

Physicochemical Information

    • Formula

    • C82H129N23O24S

    • Absent Amino Acids

    • DEHLMQSY

    • Common Amino Acids

    • T

    • Mass

    • 1853.13

    • PI

    • 9.51

    • Basic Residues

    • 2

    • Acidic Residues

    • 0

    • Hydrophobic Residues

    • 5

    • Net Charge

    • +2

    • Boman Index

    • -20.72

    • Hydrophobicity

    • -0.171

    • Aliphatic Index

    • 45.88

    • Half Life

      • Mammalian:4.4 hour
      • Yeast:>20 hour
      • E.coli:>10 hour

    • Extinction Coefficient Cystines

    • 5500

    • Absorbance 280nm

    • 343.75

    • Polar Residues

    • 9

DRAMP01053

Comments Information

    • Function

    • Has antifungal activity.

    • Induction

    • By salicylic acid and by laminarin oligosaccharides.

    • PTM

    • Contains one disulfide bond (By similarity).

Literature Information

  • ·Literature 1

    • Title

    • Purification and characterization of an antifungal thaumatin-like protein from Cassia didymobotrya cell culture.

    • Reference

    • Plant Physiol Biochem. 2006 Oct;44(10):604-610.

    • Author

    • Vitali A, Pacini L, Bordi E, De Mori P, Pucillo L, Maras B, Botta B, Brancaccio A, Giardina B.